Mistletoe (Viscum album L.) is a semi-parasitic plant that lives with several tree species, including oak, pine, fir, elm and apple, and has been used since ancient times to treat a variety of human ailments. Extracts of mistletoe have been shown to kill cancer cells in the laboratory and to stimulate the immune system.
Only the European species of mistletoe is used in the treatment of cancer. Mistletoe preparations are used to stimulate the immune system and to kill cancer cells. It has been reported to reduce tumor size and improve the quality of life and survival of some cancer patients. Three components of mistletoe (lectins, alkaloids and viscotoxins) may be responsible for its biologic effects.
A typical treatment course lasts several months to years with subcutaneous injections given early in the morning 3-7 times per week. The doses are gradually increased and adjusted depending on the patient`s general condition, sex, age, and type of cancer.
Mistletoe is typically given by subcutaneous injection, ideally near the site of the tumor while avoiding irradiated areas. It is sometimes injected directly into the tumor particularly on the liver, esophagus and cervix.
Mixed results have been obtained in animal studies that have investigated the ability of mistletoe extracts to slow tumor growth. There is no evidence from well-designed clinical trials that mistletoe or any of its components are effective treatments for human cancer.
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